The founders of Data2Bio have been employing next generation sequencing (NGS) since the early days of Roche 454 sequencing. Founded in 2010 Data2Bio was initially housed in a single room in the Iowa State University Research Incubator. Subsequently, Data2Bio developed proprietary genotyping and analytical methods adapted for Illumina and Life Technologies platforms, allowing us to grow into a contract research organization (CRO) that provides genomics, genotyping, and genomic selection services to clients focused on more than 30 species and located on six continents.
Data2Bio's proprietary tGBS® genotyping-by-sequencing (GBS) method eliminates the inefficient and temperamental adaptor molecules employed by conventional GBS and has enabled the integration of GBS directly into breeding programs that employ genomic selection, by providing accurate genotyping calls of heterozygous individuals, with turn-around times fast enough to inform crossing decisions. A combination of the built-in advantages of tGBS® genotyping and our in-house, reference-genome-free analytical pipeline makes genotyping and genomic selection possible even for orphan and nascent crops and wild species.
We assist our clients with their projects from design to execution. In a world of constant technological change, we particularly value the trust of our long-term clients.
Patrick S. Schnable is a distinguished professor and the Iowa Corn Promotion Board Endowed Chair at Iowa State University and director of ISU's Plant Sciences Institute. He is a fellow of the AAAS and a consulting editor for PLoS Genetics. His wide-ranging investigations of the maize genome have resulted in >120 peer-reviewed publications, 24 of which have been cited more than 100 times, and his work has been featured on the covers of Science and Nature Genetics. He received his BS from Cornell University and his PhD from Iowa State University and conducted post-doctoral research at the Max Planck Institute in Köln, Germany.
Sanzhen Liu is a faculty member at Kansas State University where he leads a research program focused on crop genetics and genomics. He is a co-inventor of Data2Bio's tGBS® genotyping-by-sequencing (GBS) technology and our open-source BSR-Seq gene mapping technology. His research into plant genomics and statistical methods for dealing with next generation sequencing data has produced more than 20 publications. He received his Ph.D. from Iowa State University with a major in genetics and a minor in statistics.
James C. Schnable is a faculty member at the University of Nebraska-Lincoln where he is a member of the Computational Sciences Initiative, the Center for Plant Science Innovation, and the Department of Agronomy and Horticulture. He holds degrees from Cornell University (BA) and the University of California-Berkeley (PhD). His postdoctoral studies at the Donald Danforth Plant Science Center (St. Louis, MO) and the Chinese Academy of Agricultural Sciences (Beijing, China) were supported by a fellowship from the NSF Plant Genome Research Program.
Cheng-Ting Yeh is a Bioinformatics Analyst at Iowa State University. He has degrees in computer science from Iowa State University (BS) and Oklahoma State University (MS). His research contributed in more than 20 peer-reviewed publications and has extensive experience in the development and maintenance of bioinformatic pipelines for the analysis of NGS data.